Endocrine Abstracts

Background and objective: The incidence of differentiated thyroid carcinoma (DTC) is increasing worldwide. Radioiodine (RAI) ablation is one of the main elements in the therapy of DTC after surgical removal of the gland. This study aims to compare the use of I131 in a Spanish Cohort of DTC before and after the American Thyroid Association (ATA) 2009 guidelines.Patients and methods: The Cadit-CAM study was designed to evaluate retrospectively characterist...

Background and objective: Papillary thyroid microcarcinoma (PTMC) is recognized as a separate entity by the World Health Organization. Biological behaviour and clinical outcomes of PTMC are heterogenous. Presence of lymph node metastases (LNM) in this group of patients increases the risk of recurrence and makes optimal management in PTMC controversial (observation, lobectomy with or without preventive central ipsilateral dissection). The aim of this study was to describe risk ...

Background and objective: Incidence of differentiated thyroid cancer (DTC) is increasing but not its mortality. Knowing recurrence factors is essential to plan its treatment. Recurrence related factors in our area were reviewed and compared with ATA risk stratification system.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patients diagnosed of DTC in Castilla La Mancha, a region in the central part of Spain, during ...

Background and objective: The AJCC-TNM system is optimized to predict survival in patients with cancer. Since January 2018, the new eighth edition of this staging system will be used to classify patients diagnosed of differentiated thyroid carcinoma (DTC). This study aims to compare the seventh and eighth editions of the AJCC-TNM system in a Spanish Cohort of DTC.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patien...

Introduction: Dulaglutide (Trulicity®) is a long-acting GLP-1 agonist that received US Food and Drug Administration (FDA) approval in 2014. Dulaglutide is a large sized molecule, which limits its renal clearance. This allows for once weekly dosing; which might improve patient compliance significantly. Extensive Phase III study data have been published with regard to dulaglutide, much of which was part of the AWARD studies, which provide evidence for its use in ...

Introduction: Klinefelter syndrome (KS) is the most common congenital abnormality causing primary hypogonadism. KS has a tendency for hypercoagulability.Case report: A 48 year old man diagnosed as having KS during the sterility test was admitted to our hospital emergency department after suffering a syncopal episode at work. He complained of difficulty breathing during the last two weeks and he was receiving bronchodilator therapy. He had suffered deep v...